A new review was published in Aging (listed by MEDLINE/PubMed as 'Aging (Albany NY)' and 'Aging-US' by Web of Science), on October 29, 2024, Volume 16, Issue 20, titled, 'Brain aging and Alzheimer's disease, a perspective from non-human primates.'
Aging-USNov 20 2024 A new review was published in Aging " and "Aging-US" by Web of Science), on October 29, 2024, Volume 16, Issue 20, titled, " Brain aging and Alzheimer's disease, a perspective from non-human primates."
Alzheimer's affects over 50 million people worldwide, making it crucial to understand how aging impacts the brain. This review sheds light on the differences between humans and non-human primates and reveals that while brain aging in primates involves some structural and protein changes, it does not result in the toxic protein deposits that drive Alzheimer's in humans.
Humans' unique vulnerability to Alzheimer's may be linked to traits that emerged through evolution, including larger brains, longer lifespans, and higher cognitive abilities. These adaptations may have come at a cost, making human brains more susceptible to aging-related damage. The findings also emphasize the value of studying non-human primates to understand why their brains are more resistant to severe aging-related damage. By identifying protective mechanisms in primates, researchers may discover new strategies to delay or prevent Alzheimer's in humans.
Brain Alzheimer's Disease Amygdala Antibody Blood Blood Vessels Cancer Cell Cell Biology Cortex Hippocampus Neurons Protein Research
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