A research group at LMU University Hospital has investigated how Alzheimer's disease can be diagnosed more reliably in the future.
Ludwig-Maximilians-Universitaet Muenchen Nov 25 2024 A research group at LMU University Hospital has investigated how Alzheimer's disease can be diagnosed more reliably in the future.
A new study by doctors at LMU University Hospital furnishes answers which could be incorporated into patient treatment. The study was initiated by Professor Matthias Brendel, Acting Director of the Department of Nuclear Medicine, Dr. Nicolai Franzmeier from the Institute for Stroke and Dementia Research, and Professor Günther Höglinger, Director of the Neurological Clinic - all three of whom are also members of the SyNergy Cluster of Excellence.
Method number 2 involves a technique for imaging the brain called positron emission tomography . This non-invasive method furnishes direct, semiquantitative evidence of amyloid deposits in the brain. At 1,500 to 3,000 euros per scan, however, the method is still prohibitively expensive and is not currently covered by health insurance plans.
The results showed that patients with amyloid values of over 7.1 in their CSF had PET scans that mostly did not pick up anything abnormal - meaning they tested negative for Alzheimer's. Meanwhile, patients with amyloid values of less than 5.5 in their CSF predominantly had PET scans that showed up as abnormal as well - meaning they tested positive for Alzheimer's with a high degree of probability. Most significantly, however, there was a gray area between 5.5 and 7.
Alzheimer's Disease Brain Dementia Diagnostic Drugs Hospital Imaging Research
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