A clinical trial reveals that omega-3, vitamin D, and exercise can slow biological aging, with combined interventions showing the strongest effects on health.
By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Danielle Ellis, B.Sc.Feb 3 2025 An analysis of a clinical trial involving 777 older adults suggests that daily omega-3 intake can moderately slow biological aging, with combined interventions showing the strongest effects on aging and disease prevention
Background Biological aging is the progressive deterioration of physiological functions in living organisms. A vast pool of studies have been conducted on animals and humans to understand the aging process and to identify interventions aimed at slowing down biological aging. The DO-HEALTH trial was a multicenter randomized controlled trial designed to support healthy longevity. Its primary aim was to investigate the effect of vitamin D and omega-3 supplementation and exercise, either individually or in combination, over three years.
Related StoriesThey controlled potential covariates in the analysis and found that these changes in DNA methylation measures of biological aging are not dependent on the age, sex, and body mass index of participants. The study finds a small protective effect of omega-3 supplementation on slowing down biological aging over three years across several epigenetic clocks. Furthermore, the study finds that these three interventions together have the highest impact in reducing cancer risk and preventing frailty over 3 years.
Among the epigenetic clocks analyzed, the study finds the strongest effect on two second-generation clocks and one third-generation clock, which is in accordance with previous studies investigating the effects of lifestyle factors on biological aging.
Cancer Clinical Trial DNA DNA Methylation Exercise Vitamin D
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
King Charles Revives Political Tradition with One-to-One Meeting with Conservative LeaderKing Charles III met with Conservative leader Kemi Badenoch in a formal one-to-one audience at Buckingham Palace, reviving a political tradition that had been dormant for nearly two decades. This follows a period where the convention of the monarch meeting with opposition leaders was largely abandoned. The meeting comes amidst ongoing discussions about the King's role in political matters and his commitment to environmental causes.
Read more »
Devon rowing teams battle flying fish in Atlantic crossingOne team member was hit five times in one night by the 'smelly' fish.
Read more »
Dramatic moment Ukrainian drone destroys 3 Russian UAVs with built-in SHOTGUNWatch Ukraine’s newest drones use built-in SHOTGUNS to down Russian targets one by one
Read more »
Villagers fume over potholes and joke 'we don't need speed limits'One local says he has reported more than 500 potholes in one month
Read more »
Peterborough City Council will sell Mooncups for £5The authority says in one year, one Mooncup can replace 264 single-use menstrual products.
Read more »
Amazon slashes £10 off Tamnavulin Speyside Single MaltOne five-star review said: 'One of my go to drams this winter I reckon'.
Read more »