A research team at the University of Konstanz, led by toxicologist Ivano Amelio, has demonstrated how differently individual mutations of the tumor suppressor p53 affect pancreatic carcinomas.
University of KonstanzDec 6 2024
How p53 works In case of DNA damage, the p53 protein has the task of blocking the proliferation of the affected cell, thus providing extra time for repairs. Should this repair fail, the cell self-destructs and makes room for a new one that is as flawless as possible. This process is important to ensure that only healthy cells multiply and that uncontrolled proliferation does not occur.
Research Carcinomas Cell Cell Death Cell Division Malignant Metabolism Mutation P53 Protein Proliferation Protein
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