Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed.
University of California - San FranciscoJul 3 2024 Progressive supranuclear palsy , a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed. But now, UC San Francisco researchers have found a way to identify the condition while patients are still alive.
The disorder crossed the public's radar 25 years ago, when Dudley Moore, the star of "10" and "Arthur," shared his PSP diagnosis. It is frequently mistaken for Parkinson's disease, but PSP develops faster, and patients do not respond to treatments for Parkinson's. Most PSP patients die within about seven years after their symptoms have started.
"When new medications are approved for PSP, the best chance for patients will be receiving treatment at the earliest phase of the disease when it is most likely to be effective," he said. The researchers measured the protein biomarkers using the high-throughput technology for protein analysis, which is based on molecules that bind to proteins with high selectivity and specificity.
Alzheimer's Disease Blood Children Dementia Diagnostic Frontotemporal Dementia Hospital Neurodegeneration Neurology Parkinson's Disease Progressive Supranuclear Palsy Protein Research Technology
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