New research into a chemical produced by a caterpillar fungus that has shown promise as a possible cancer treatment has revealed how it interacts with genes to interrupt cell growth signals.
University of NottinghamNov 7 2024 The discovery is an important step towards developing new drugs for the treatment of the disease.
Scientists from the University of Nottingham's School of Pharmacy have been studying how a parasitic fungus that grows on caterpillars could work as a potential treatment for a range of diseases by studying cordycepin, one of the drugs found in these mushrooms. The research has been published in the journal FEBS Letters.
Using high-throughput techniques the research team measured the effects of cordycepin on the activity of thousands of genes in multiple cell lines. The research compared the effects of cordycepin with those from other treatments deposited in databases and showed that it works by acting on the growth inducing pathways of the cell in all cases.
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