Researchers found found that as people's arousal levels dwindle during an fMRI, such as if they become more relaxed and sleepy, resulting changes in breathing and heart rates alter blood oxygen levels in the brain, which are then falsely detected on the scan as neuronal activity.
Researchers found found that as people's arousal levels dwindle during an fMRI, such as if they become more relaxed and sleepy, resulting changes in breathing and heart rates alter blood oxygen levels in the brain, which are then falsely detected on the scan as neuronal activity. The researchers then developed a method, called RIPTiDe, to mitigate this problem.
"You're laying down in a snug scanner for quite some time, often with only a low-engagement button press task to attend to or nothing to do at all, as the scanner monotonously hums and vibrates around you," said first author Cole Korponay, PhD, a research fellow at the McLean Hospital Imaging Center.
"By adopting this sLFO denoising procedure, future studies can mitigate the distortive effects of arousal changes during brain scans and enhance the validity and reliability of fMRI findings," said Korponay.
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