Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack-;blocking the energy supply T cells depend on.
Weill Cornell Medicine Oct 23 2024 The work, published Oct . 23 in Nature, points toward a promising new immunotherapy approach for ovarian cancer , which is notoriously aggressive and hard to treat.
Dr. Juan Cubillos-Ruiz, Senior Author, The William J. Ledger, M.D., Distinguished Associate Professor of Infection and Immunology in Obstetrics and Gynecology, Weill Cornell Medicine Working with collaborators, the researchers used a battery of biochemical assays to identify proteins that bind to FABP5. They found a protein called Transgelin 2 that interacts with FABP5 and helps move it to the cell surface.
Ovarian Cancer Blood Blood Vessels Cell Cytoplasm Gene Immune System Immunotherapy Lipids Medicine Micrograph Mitochondria OCT Protein Research Transcription Tumor
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