Researchers propose the tools and frameworks of EBM+ to help overcome the COVID-19 pandemic bmj_company UniofOxford UofT UNSW COVID19 coronavirus covid pandemic medicine evidencebasedmedicine
By Neha MathurNov 29 2022Reviewed by Danielle Ellis, B.Sc. In a recent article published in BMJ, researchers proposed the tools and frameworks of mechanistic evidence, sometimes known as evidence-based medicine + combined with traditional EBM, might help overcome the highly protracted coronavirus disease 2019 pandemic.
SARS-CoV-2 has proved tenacious and shifting. While RCTs and meta-analyses of RCTs remarkably estimated the efficacy of COVID-19 drugs and vaccines, some scholars argue that tackling some of its aspects critically required mechanistic evidence. COVID-19 led to complex situations where multiple variables interacted dynamically with high uncertainty.
Indeed, RCTs are not a panacea; thus, systemic reviews are crucial to interpret primary evidence along with modifications of the hierarchy of evidence to answer contemporary policy questions pertaining to SARS-CoV-2. Lab Diagnostics & Automation eBook Compilation of the top interviews, articles, and news in the last year. Download a copy today Early in the pandemic, COVID-19 scientific research was prematurely fixed and constrained to a population-intervention -comparison-outcome format that narrowed predefined outcomes and suppressed scientific imagination. Such studies estimated infections in the mask wearer in statistical terms.
i) real-world case studies and mathematical modeling studies supporting airborne route of transmission of SARS-CoV-2iii) Psychological and socio-cultural evidence of whether people wear masks
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