A vascular 'fingerprint' on the light sensitive tissue layer at the back of the eye-the retina-can predict a person's risk of stroke as accurately as traditional risk factors alone, but without the need for multiple invasive lab tests, finds research published online in the journal Heart.
BMJ GroupJan 13 2025 A vascular 'fingerprint' on the light sensitive tissue layer at the back of the eye-the retina-can predict a person's risk of stroke as accurately as traditional risk factors alone, but without the need for multiple invasive lab tests, finds research published online in the journal Heart .
The retina's intricate vascular network is known to share common anatomical and physiological features with the vasculature of the brain, making it an ideal candidate for assessing damage from systemic ill health, such as diabetes, explain the researchers. To explore this further, they measured 30 indicators across 5 categories of retinal vascular architecture in fundus images from 68,753 UK Biobank study participants.
The final analysis included 45,161 participants . During an average monitoring period of 12.5 years, 749 participants had a stroke. Each change in density indicators was associated with an increased stroke risk of 10-19%, while similar changes in calibre indicators was associated with an increased risk of 10-14%.
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