Scientists uncover new MRSA resistance mechanism

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Scientists uncover new MRSA resistance mechanism
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Scientists have discovered the mechanism which allows the superbug Methicillin Resistant Staphylococcus aureus (MRSA) to become highly resistant to antibiotics, paving the way for new approaches to control infectious disease.

University of SheffieldNov 1 2024 Scientists have discovered the mechanism which allows the superbug Methicillin Resistant Staphylococcus aureus to become highly resistant to antibiotics, paving the way for new approaches to control infectious disease.

The new research, led by the University of Sheffield, reveals MRSA has a double defence mechanism against antibiotics - this new insight offers hope in treating the life-threatening superbug and other infectious diseases. It has been known for many years that in order to be resistant, MRSA has acquired a new cell wall enzyme that allows it to survive exposure to antibiotics. However, the Sheffield researchers have found that this alone is insufficient for survival.

This research is very exciting as it has not only uncovered a new mechanism for MRSA, that was hiding in plain sight, but also the ability of the bacteria to divide in an alternative way. These findings have important ramifications for the development of new antibiotics, but also for understanding the fundamental principles that underpin bacterial growth and division. This will provide new ways to tackle this dangerous infectious organism.

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