Spit test ‘better than blood test for men with genetic prostate cancer risk’

Early research raises hopes of a more accurate screening tool for men who are at high risk of aggressive disease.

A prostate cancer spit test is better for men with higher genetic risk than a standard blood test, research suggests

The saliva test, where the sample can be collected at home, looks for genetic variants linked to prostate cancer. The researchers calculated the polygenic risk score – which is based on 130 genetic variations in the DNA code linked to prostate cancer – of all those taking part. In case of PSA tests, only 25% of men with a high PSA level will actually have prostate cancer, the researchers said.

“We know that the current PSA test can cause men to go through unnecessary treatments and, more worryingly, it’s missing men who do have cancer.“This research is a promising step towards that goal, and it highlights the role that genetic testing can play in saving lives.”

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