Lichuan Wu et al., at Medical College of Guangxi University, China, presented a comprehensive study on the role of replication factor C subunit 4 (RFC4) in nasopharyngeal carcinoma (NPC), a type of epithelial cancer commonly associated with Epstein-Barr virus infection.
Frontiers JournalsJul 12 2024 Lichuan Wu et al., at Medical College of Guangxi University, China, presented a comprehensive study on the role of replication factor C subunit 4 in nasopharyngeal carcinoma , a type of epithelial cancer commonly associated with Epstein-Barr virus infection. The research was conducted with the aim of understanding the pathogenesis of NPC and identifying potential therapeutic targets.
The research utilized a multi-faceted approach involving bioinformatics analysis, cell culture, transfection assays, plate cloning formation assays, cell cycle detection, RNA extraction and real-time qPCR, RNA sequencing, western blot, and a nude mouse xenograft model. The study also included statistical analysis to measure the correlation between RFC4 and other genes, and to compare different experimental groups.
Cell Cell Proliferation In Vitro In Vivo Nasopharyngeal Proliferation Bioinformatics Cancer Cell Cycle Epstein-Barr Virus Gene Research RNA Virus
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