Study links fetal acetaminophen exposure to increased risk of ADHD

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Study links fetal acetaminophen exposure to increased risk of ADHD
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Fetal acetaminophen exposure increases the likelihood that a child will develop attention-deficit/hyperactivity disorder (ADHD), according to a study published Feb. 6 in Nature Mental Health.

University of Washington School of Medicine /UW Medicine Feb 21 2025 Fetal acetaminophen exposure increases the likelihood that a child will develop attention-deficit/hyperactivity disorder , according to a study published Feb. 6 in Nature Mental Health .

"This medication was also approved decades ago, and may need reevaluation by the FDA," said Sathyanarayana, the paper's senior author. "Acetaminophen was never evaluated for fetal exposures in relations to long-term neurodevelopmental impacts." Related StoriesAcetaminophen metabolites were detected in 20.2% of maternal plasma samples. Children whose mothers had these biomarkers present in their plasma had a 3.15 times higher likelihood of an ADHD diagnosis compared with those without detected exposure.

Mothers often are advised to turn to acetaminophen, the primary agent in Tylenol, rather than ibuprofen, which is more likely to adversely affect the fetal kidney or heart, Baker said. So, what is a mother to do?

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