Epigenetics, the chemical mechanisms that controls the activity of genes, allows our cells, tissues and organs to adapt to the changing circumstances of the environment around us.
Reviewed by Megan Craig, M.Sc.Nov 2 2023 This advantage can become a drawback, though, as this epigenetic regulation can be more easily altered by toxins than the more stable genetic sequence of the DNA.
The publication is led by Dr. Christopher J. Chang, of the University of California Berkeley in the United States, whose research group is pioneer in the study of the effects of various chemical products on cell metabolism. The research has focused on investigating the effects of high concentrations of formaldehyde in the body, a substance already been associated with an increased risk of developing cancer , hepatic degeneration due to fatty liver and asthma. Dr.
As an overview of the research, Dr. Esteller points out that "we have discovered that formaldehyde is an inhibitor of the MAT1A protein, which is the main producer of S-Adenosyl-L-Methionine and this last molecule is the universal donor of the chemical group "methyl" that regulates epigenetic activity.
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