With about 214,110 traumatic brain injuries (TBIs) and over 69,000 TBI-related deaths in 2021 according to the Centers for Disease Control and Prevention (CDC), understanding the physical and mental consequences of TBI is critical for study.
University of New MexicoSep 16 2024 With about 214,110 traumatic brain injuries and over 69,000 TBI-related deaths in 2021 according to the Centers for Disease Control and Prevention , understanding the physical and mental consequences of TBI is critical for study.
Registered reports like this are a nice option where the whole peer review team and the editor know it is an important question and a rigorous study design ahead of time. No matter what happens with it, by accepting the initial Stage 1 Registered Report they agree it will be worth publishing the results in Stage 2 whether or not there is a big effect. That's what we did here.
In this new Report, Hogeveen and colleagues took advantage of an ongoing NIH-funded study called the Adolescent Brain Cognitive Development study. This large-scale study began between 2016 and 2018, enrolling over 10,000 children aged 9-10 for initial brain scans and neuropsychological assessments. These participants will continue to undergo follow-up assessments and brain scans every two years until they are 18-19 years old, with data collection concluding in 2027.
Related StoriesIn contrast, in this pre-registered prospective analysis, Hogeveen and colleagues identified 43 ABCD study participants that had no brain injury history at baseline, but experienced a mild TBI 3-24 months prior to their follow-up ABCD study visit. They then identified a group of 43 "control" participants that were demographically-matched to the mTBI group, and had levels of cognitive functioning and depression that were identical to mTBI group at baseline.
At this stage, Hogeveen is careful to point out that this study does not say anything about the potential consequences of more severe TBI in youth, or mild TBI in adults-;either of which may be more likely to cause depression than what the team found in the current study.
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