Study suggests saliva samples may be better indicators of SARS-CoV-2 persistence than nasal swabs SARSCoV2 Coronavirus Disease COVID Saliva Virustesting PLOSONE Rutgers_NJMS
Accurate and rapid SARS-CoV-2 infection diagnosis has proven to be critical in coronavirus disease 2019 management. Salivary and nasal swabs are some popularly employed non-invasive methods for testing infection with minimal to no supervision, thus enabling the widespread activity of COVID-19 testing. Several studies performed on nasal and pharyngeal samples noted a reduction in viral shedding along with a decline in culturable virus within the first week of COVID-19 symptoms.
The team compared viral load dynamics associated with salivary and nasal specimens by performing a substudy in an observational group study of therapeutic and diagnostic techniques among COVID-19 patients. Eligible participants were patients who were enrolled at University Hospital, New Jersey. These participants were aged 18 years or older and tested SARS-CoV-2-positive by a nasopharyngeal swab and consented to provide nasal and saliva samples.
Related StoriesAmong 96 participants from the overall analysis group, the mean patient age was 54.7 years, including 53% male and 55% Hispanic persons. The average baseline sample collection occurred seven days post-symptom onset. A majority of the participants reported a minimum of one comorbidity, such as obesity or hypertension, were exposed to another person having SARS-CoV-2 symptoms or required supplemental oxygen during their hospital stay.
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