The brain's cannabinoid system protects against addiction following childhoodmaltreatment, study shows MolPsychiatry
Childhood maltreatment has long been suspected to increase the risk of developing a drug orlater in life. Researchers at Linköping University have previously shown that this risk is three times higher if you have been exposed to childhood maltreatment than if you have not, even when accounting for confounds from genetics and other familial factors.
Endocannabinoids, i.e. the body's own cannabis-like substances, are an interesting player in this context. Theplays an important part in regulating reactions to stress and discomfort. Recent research suggests that this endogenous system may function as a stress buffer. The researchers behind the study aimed to investigate possible mechanisms behind susceptibility or resilience to developinglater in life after exposure to childhood maltreatment. One difficulty in research is that people who develop problems later in life tend to overreport negative life experiences when questioned about earlier events.
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