In hospital operating rooms and intensive care units, propofol is a drug of choice, widely used to sedate patients for their comfort or render them fully unconscious for invasive procedures.
Michigan Medicine - University of MichiganSep 10 2024
Consciousness has been the subject of study from various perspectives and understanding the neurobiological foundations of consciousness carries major implications of multiple medical disciplines such as neurology, psychiatry and anesthesiology." A new study published in the journal Nature Communications and led by Huang, George Mashour, M.D., Ph.D. and Anthony G. Hudetz, Ph.D., of the U-M Center for Consciousness Science outlines for the first time in humans how the connections among brain cells within those two important areas are modified by propofol.
Related StoriesThe team found that, under deep sedation, the thalamus showed a drastic reduction in activity in clusters of brain cells responsible for transmodal processing leading to a dominant unimodal pattern-;suggesting that while sensory inputs are still received, there is no integration of those inputs.
Anesthesiology Cell Cortex Hospital Intensive Care Medicine Neurology Ph Psychiatry Thalamus
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