Viruses like SARS-CoV-2 don't respect boundaries, moving between species and continents and leaving destruction as they go. Beating the next pathogen with pandemic potential means getting good at crossing borders ourselves -; between fields of study, between research universities, and between scientists and the wider community.
Virginia TechAug 23 2024 Virus es like SARS -CoV-2 don't respect boundaries, moving between species and continents and leaving destruction as they go. Beating the next pathogen with pandemic potential means getting good at crossing borders ourselves -; between fields of study, between research universities, and between scientists and the wider community.
Cornell University, the University of Michigan, Meharry Medical College, and Wake Forest University also will collaborate to meet the critical challenge of thwarting infectious diseases that threaten the global community. T.M. Murali, associate department head for research in the Department of Computer Science will direct the new center.
The majority of emerging human viruses originate from wildlife and domestic animal species. "There are many challenges in trying to determine if a virus that currently infects one or more animals can jump to humans, and when that leap can lead to a pandemic," Murali said. "What we are focusing on is really trying to understand how a pathogen or a virus can shift to a new host and how it interacts with a host at a cellular, organ, or the whole body," Murali said.
"With colleagues at Cornell University and the University of Michigan, we will attempt to predict, through novel machine learning systems, which viruses will jump from animals to humans, and which specific mutations within the viral genome may enable these shifts. We will also experimentally validate the computational predictions through biological studies using human organoid cultures," Meng said.
Persisting in the environment University Distinguished Professor Linsey Marr in the Charles Edward Via, Jr. Department of Civil and Environmental Engineering and collaborators at the University of Michigan will seek to discover what helps emerging pathogens grow and survive and what conditions can arrest their spread.
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