Do taste genes influence how much alcohol we drink and our body fat?

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Do taste genes influence how much alcohol we drink and our body fat?
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Study examines how polymorphisms in bitter taste receptor genes relate to alcohol consumption and body fat percentage, revealing significant associations with TAS2R13 but not TAS2R38.

By Dr. Priyom Bose, Ph.D.Jun 9 2024Reviewed by Benedette Cuffari, M.Sc. A recent Nutrients journal study explores the association between polymorphisms in the bitter taste receptor genes, alcohol consumption, and body fat percentage.

Previous research has reported that the TAS2R38 gene mediates the bitter taste of thiourea compounds like phenylthiocarbamide and 6-n-propylthiouracil . Both are synthetic compounds structurally similar to bitter compounds found in cruciferous vegetables, leafy greens, and certain herbs and spices. The TAS2R13 gene also corresponds to bitter taste.

Related StoriesData were obtained between February 2016 and November 2020. All study participants completed a food frequency questionnaire that provided information on food intake and portion sizes over the last year. One prior study on head and neck cancer patients reported a significant association between alcohol consumption and rs1015443. Another study noted that the intensity of ethanol taste in the mouth is related to TAS2R13 .

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