Glioblastomas are aggressive brain tumors with a median survival time of less than 22 months despite standard therapy including surgery, irradiation, and chemotherapy.
International Society for Stem Cell ResearchOct 17 2024 It has become clear in recent years that not all cells within the brain tumor have an equal potential to divide and drive tumor growth. As such, a fraction of tumor cells called brain tumor stem cells are thought to be the primary origin of tumor re-growth after surgery in addition to being resistant to standard treatments including chemotherapy and irradiation. Therefore, targeting BTSCs may be a way to effectively treat glioblastomas.
In an effort to rapidly identify new treatments effective against BTSCs, a team of researchers from the University of Ottawa, Canada, tested Edaravone, an FDA-approved drug, for its efficacy against BTSCs, knowing that Edaravone blocks cellular processes which are important for the growth and survival of BTSCs.
Brain Tumor Cell Chemotherapy Glioblastoma Stem Cells Surgery Tumor
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