Men taking epilepsy drug valproate warned to use effective contraception

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Men taking epilepsy drug valproate warned to use effective contraception
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A regulator says new evidence shows children born to men taking the drug valproate are more likely to have neurodevelopment problems, including autism, ADHD, and tic or learning disorders. The drug had previously been linked to disorders and birth defects born to women taking it.

Thousands of men taking a drug for epilepsy or bipolar disorder - and their partners - have been warned to use effective contraception because any babies they conceive may be at increased risk of harm. The Medicines and Healthcare products Regulatory Agency says new evidence shows children born to men taking the drug valproate are more likely to have neurodevelopment problems, including autism, ADHD, and tic or learning disorders.

Dr Alison Cave, chief safety officer at the MHRA, said: 'While the risk to a child is lower than the risk associated with a mother taking valproate in pregnancy, we recommend that men taking valproate and their partners follow the updated guidance and use effective contraception. 'Patients on valproate should not stop taking their medicine unless advised to do so by a healthcare professional.

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