New study evaluates the safety profile of the BNT162b2 vaccine in New Zealand minhealthnz SARSCoV2 COVID19 Vaccine BNT162b2
By Neha MathurJan 24 2023Reviewed by Aimee Molineux In a recent study posted to the Preprints with The Lancet* server, researchers determined the association between adverse events of special interest following BNT162b2 vaccination, a coronavirus disease 2019 vaccine based on the messenger ribonucleic acid technology.
Additionally, New Zealand's demographics are unique because it mainly has three minority ethnic groups, Māori , Pacific islanders, and Asians. It makes it crucial to assess the safety profile of BNT162b2 in a New Zealand-specific context, which clinical trials could not have deciphered. The study population comprised New Zealanders aged five or above who received a primary dose of the adult and pediatric BNT162b2 formulation. This study estimated the incidence per 100,000 persons, per year, of 12 predefined AESI associated with COVID-19 vaccines, stratified by year, age group, gender, ethnicity, et cetera.
Among the second dose recipients, the researchers noted 1.3 and 1.2 events of thrombocytopenia and venous thromboembolism . Though the observed events were more than expected, the rate upsurges were small, and the confidence intervals were near one, suggesting a minimal difference between the two events. While VTE increased slightly following the first BNT1262b dose in the 40–59-year-olds, there was no substantial increase in thrombocytopenia events in any subgroup.
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