Nonanemic Iron Deficiency Underdiagnosed in Women

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Nonanemic Iron Deficiency Underdiagnosed in Women
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ID affects about two billion people worldwide, mainly women and children, increasing risk for fatigue, impaired muscular performance, and adverse pregnancy outcomes.

Three different definitions of nonanemic iron deficiency , a common disorder causing substantial morbidity in women, were significantly associated with different population prevalence estimates, a data analysis of the cross-sectional Hemochromatosis and Iron Overload Screening Study study found.

"Using higher serum ferritin thresholds to define ID could lead to diagnosis and treatment of more women with ID and greater reduction of related morbidity," the investigators wrote. TheThe authors noted that ID affects about two billion people worldwide, mainly women and children, increasing risks of fatigue, impaired muscular performance, cold intolerance, mucosal and epithelial abnormalities, pica, disturbances of menstruation, and adverse pregnancy outcomes.

In data for the current study analyzed from June to December, 2023, the three ID definitions were: combined transferrin saturation less than 10% and SF less than 15 ng/mL ; SF less than 15 ng/mL ; and SF less than 25 ng/mL, the threshold for ID-deficient erythropoiesis .

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