Pediatric SARS-CoV-2 seroprevalence higher than official case reports Coronavirus Disease COVID SARSCoV2 CDC_NCEZID ChildrensColo
By Neha MathurApr 3 2023Reviewed by Benedette Cuffari, M.Sc. In a recent article published by the United States of America Centers for Disease Control and Prevention Emerging Infectious Diseases online journal, researchers conducted a cross-sectional survey to estimate severe acute respiratory syndrome coronavirus 2 antibodies in children with confirmed coronavirus disease 2019 between May and July 2021 in Colorado.
About the study In the present study, researchers first collected residual serum samples from all eligible children. Then, these samples were tested for SARS-CoV-2 nucleocapsid and spike IgG using qualitative enzyme-linked immunosorbent assay . Study findings The final study sample comprised 829 children, 422 of whom were female, with an average age was nine years. A total of 940 distinct residual serum samples were obtained from these children aged between one to 17 years during the spring/summer season of 2021.
In rounds 20 and 21 of the aforementioned nationwide survey, the estimated seroprevalence was 13.4% and 17.5%, respectively. However, the findings of round 25 showed a seroprevalence of 40.1%, which was much more comparable to the current study results.
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