A recent study published in The Journal of Nutrition shows that SARS-CoV-2 infection significantly alters the composition of human milk, impacting lipid and metabolite profiles. However, vaccination against COVID-19 does not appear to have the same effect, assuring the safety of breastfeeding mothers and their babies.
By Vijay Kumar MalesuReviewed by Susha Cheriyedath, M.Sc.Dec 19 2024 Cutting-edge research shows SARS-CoV-2 infection disrupts milk composition, but vaccines ensure safety for breastfeeding moms and their babies.
Human milk is the gold standard for infant nutrition, offering essential nutrients, immune cells, and immunomodulatory components that protect infants with immature immune systems. While it reduces infections, it can transmit certain pathogens such as human immunodeficiency virus and Ebola virus. Milk was self-collected at specific intervals before and after vaccination using clean containers, with collection procedures approved by the Mount Sinai Hospital Institutional Review Board . For participants with SARS-CoV-2 infection, milk samples were collected within seven days of a confirmed positive test, with collection procedures approved by the University of Idaho IRB.
Study participants ranged from 26 to 41 years old, with a mean age of 32 years, and were between less than one month to 30 months postpartum, with a mean of 8 months postpartum. In contrast, COVID-19 vaccination resulted in minimal changes to milk composition. No significant alterations were observed in milk lipidomics or metabolomics across any of the vaccine types evaluated. Proteomic changes varied by vaccine and timing.
COVID-19 Breastfeeding Human Milk SARS-Cov-2 Vaccination
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