A team of researchers led by City of Hope scientists has identified a type of regulatory T cell that can regenerate the thymus, a gland crucial for immune system function. This discovery could lead to new treatments for patients whose thymus is damaged by cancer therapies, aging, or stress.
A team of international researchers, led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, have made a groundbreaking discovery in the field of immunology. Published today in the journal Immunity, their study reveals a novel pathway for thymus regeneration.
The thymus, a small gland situated between the lungs and in front of the heart, plays a crucial role in human health by producing T cells, the key components of our immune system. In cancer patients, certain therapies, along with aging and stress, can deplete T cell output, leaving individuals vulnerable to infections and other diseases. The research team identified a specific type of regulatory T cell (Treg) that can home back to the thymus and repair the organ when damaged. This discovery represents a paradigm shift in our understanding of thymus function and opens up exciting new possibilities for treating thymic fatigue and damage.
IMMUNE SYSTEM THYMUS CANCER THERAPIES REGULATORY T CELLS REGENERATION
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