Pharmaceutical companies are increasingly relying on advanced, data-driven strategies to ensure consistent product quality and high efficiency. Bruker's Fourier PAT integrates nuclear magnetic resonance (NMR) into process analytical technology (PAT) frameworks, offering real-time analysis of critical quality attributes (CQAs) and enabling process optimization. This technology, combined with Optimal Industrial Technologies' synTQ platform, provides quantitative and qualitative data, supports continuous processing, and facilitates spontaneous process control.
Sponsored Content by Bruker BioSpin - NMR , EPR and ImagingReviewed by Olivia FrostJan 22 2025 Pharmaceutical companies must use advanced, data-driven strategies to stay competitive while ensuring consistent product quality, high efficiency, and peak productivity.
Bruker’s Fourier PAT integrates nuclear magnetic resonance into PAT orchestrations. It perfectly complements development and advanced manufacturing settings requiring reliable process control. NMR is a primary method that provides quantitative and qualitative data. It does not require validated reference material and its data can be utilized directly to adjust other spectroscopies instantly. It can substitute offline adjustment tools and be employed synergistically with infrared , saving substantial time.
The optimum solution for advanced manufacturing The Fourier PAT supports numerous operations modes, from at-line automation to flow and stop-flow measurements, as well as online/flow modality, which facilitates spontaneous process optimization and control. The PIPAc project, funded by Bpifrance, aims to further advance API manufacturing by creating an independently piloted chemical micro-plant for molecule production driven by flow chemistry, AI, and additive manufacturing .
NMR PAT Pharmaceutical Manufacturing Process Optimization Data-Driven Strategies
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